The record
| Class | amylin analog |
|---|---|
| Also known as | AM833, NN9838, NN0174-0833, long-acting amylin analogue |
| Chain length | 37 residues |
| Molecular weight | 4,409.01 Da |
| Half-life | ~7-8 days (once-weekly dosing; acylated, albumin-bound) |
| Route | SC |
| Studied for | - |
| Research use | - |
| What has been shown | - |
| How it works | Long-acting acylated amylin analogue; non-selective agonist at amylin receptors (AMY1-3) and the calcitonin receptor. Slows gastric emptying, promotes satiety; developed for weight management, especially co-administered with semaglutide (CagriSema). Acylation confers albumin binding and once-weekly dosing. |
| Patent status | - |
| Regulatory status | - |
Blank = not established in the record. Nothing is estimated to fill a gap.
Where it is matched
- Appetite Regulation Environment (affection, 56%)