The record
| Class | hormone |
|---|---|
| Also known as | GnRH, LHRH, Factrel, Lutrelef |
| Chain length | - |
| Molecular weight | 1,182.3 Da |
| Half-life | 2-4 minutes (distribution); 10-40 minutes (terminal) |
| Route | IV, SC, or IM |
| Studied for | Diagnostic testing of pituitary function, Pulsatile therapy for hypogonadotropic hypogonadism (requires pump) |
| Research use | PCT protocols, Fertility research, Endocrine testing |
| What has been shown | Stimulates LH/FSH release; Restores fertility (pulsatile); Diagnostic tool for pituitary function; PCT recovery aid (limited use) |
| How it works | Hypothalamic releasing hormone that stimulates LH and FSH release from anterior pituitary. Pulsatile administration maintains receptor sensitivity and supports reproduction. Continuous administration causes receptor downregulation and HPG axis suppression. |
| Patent status | Generic available |
| Regulatory status | FDA approved (diagnostic use) |
Blank = not established in the record. Nothing is estimated to fill a gap.
Where it is matched
- HPG Axis Signaling Support (affection, 81%)
- Hypogonadotropic hypogonadism (illness, 60%)
- Hypothalamic amenorrhea (illness, 60%)
- IVF oocyte maturation trigger (illness, 60%)
- PCOS treatment (illness, 60%)
- Pulsatile therapy for hypogonadotropic hypogonadism (illness, 100%)
- Low libido (symptom, 50%)