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Cognitive Enhancement / Focus

From the engine's documented indication list (thirty entries, curated 2026-02-23). Targets: synaptic plasticity 70%, cholinergic support 55%, BDNF modulation 55%, neuroprotection 50%, arousal modulation 35%.

Matched peptides

Highest match first. The score is the share of this entry's targets the peptide carries; it is a match score, not a verdict.

PeptideHow it worksWhy it matches
Dihexa
Nootropic & neuro
Small molecule peptidomimetic derived from angiotensin IV. Binds hepatocyte growth factor (HGF) and its receptor c-Met with high affinity. Promotes: (1) HGF/c-M...synaptic plasticity, BDNF modulation, neuroprotectionCompare & quote
NA-Semax
Nootropic & neuro
N-acetylated heptapeptide analog of ACTH(4-10) with Pro-Gly-Pro added for stability. Enhances BDNF/TrkB signaling up to 500%, increases hippocampal neurogenesis...synaptic plasticity, BDNF modulation, neuroprotectionCompare & quote
Semax
Nootropic & neuro
BDNF increase; Enkephalin modulation; Dopamine/serotonin regulationsynaptic plasticity, BDNF modulation, neuroprotectionCompare & quote
P21
Nootropic & neuro
Neurogenesis stimulation; Dendritic growth; AMPA receptor modulationsynaptic plasticity, BDNF modulationCompare & quote
Cerebrolysin
Nootropic & neuro
Complex mixture of 14,635 peptides (<10 kDa) from porcine brain. 25% peptides, 75% free amino acids. Contains fragments of tubulin, actin, myelin basic protein,...BDNF modulation, neuroprotectionCompare & quote
NA-Selank
Nootropic & neuro
N-acetylated version of Selank with enhanced stability and potentially different receptor binding. Anxiolytic heptapeptide derived from tuftsin with added Pro-G...BDNF modulationCompare & quote
ARA-290
Nootropic & neuro
Synthetic 11-amino acid peptide derived from the helix-B domain of erythropoietin (EPO). Selectively activates the innate repair receptor (IRR), a heteromer of ...neuroprotectionCompare & quote
BPC-157
Nootropic & neuro
Synthetic peptide based on body protection compound from gastric juice. Pleiotropic effects: (1) Upregulates growth factor receptors, (2) Promotes angiogenesis ...neuroprotectionCompare & quote
Cortagen
Nootropic & neuro
Khavinson tetrapeptide identified as a primary active component of Cortexin (bovine brain cortex peptide preparation); studied for neuroprotection and nerve rep...neuroprotectionCompare & quote
Humanin
Nootropic & neuro
Reported cytoprotective peptide with anti-apoptotic signaling; described as interacting with apoptosis-related pathways and having neuroprotective and metabolic...neuroprotectionCompare & quote
L-Carnosine
Nootropic & neuro
Endogenous dipeptide found abundantly in muscle and brain tissue. Functions as intracellular buffer (histidine imidazole ring), antioxidant (metal chelation, RO...neuroprotectionCompare & quote
PEG-MGF
Growth hormone axis
PEG-MGF is a PEGylated splice variant of IGF-1 (IGF-1Ec). It activates muscle satellite cells (muscle stem cells), causing them to proliferate and fuse with exi...neuroprotectionCompare & quote

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For the peptides you pick it lists the products vendors in your country offer, each clickable, and ranks them three ways: best price (product price per mg), best value (price per mg after the water, syringes or needles the format forces), and best overall (value, days usable after opening, handling and quantity, weighted in the open). Every number's working is printed under it.

How the arithmetic works