The record
| Class | immunomodulator |
|---|---|
| Also known as | KE dipeptide, Lysylglutamic acid, Lysylglutamate, Normophthal |
| Chain length | - |
| Molecular weight | 275.3 Da |
| Half-life | Very short (dipeptide - minutes) |
| Route | SC |
| Studied for | Immune deficiency; Age-related immune decline; Tissue regeneration; Cancer prevention |
| Research use | Immunomodulation; Anti-aging/geroprotection; Epigenetic regulation |
| What has been shown | Enhances T-cell function; Reduces spontaneous tumor incidence by ~50%; Extends lifespan in animal models; Accelerates tissue regeneration |
| How it works | Shortest peptide known to have biological activity - just two amino acids. Derived from thymus tissue (component of Thymalin). Acts as epigenetic regulator - induces chromatin deheterochromatinization, reactivating silenced genes. Activates interleukin-2 signaling in splenocytes, stimulates CD4 and CD5 T-cell differentiation, enhances CD8 cytotoxic T-cell function. Increases intracellular Ca2+ in |
| Patent status | Russian patents |
| Regulatory status | research; dietary supplement (Russia) |
Blank = not established in the record. Nothing is estimated to fill a gap.
Where it is matched
- Proteostasis / Cellular Cleanup (affection, 37%)
- Senescence Modulation (Research) (affection, 79%)
- Age-related immune decline (illness, 100%)
- Cancer prevention (illness, 100%)
- Immune deficiency (illness, 100%)
- Tissue regeneration (illness, 100%)
- Frequent infections (symptom, 50%)