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Senescence Modulation (Research)

From the engine's documented indication list (thirty entries, curated 2026-02-23). Targets: senescence modulation 85%, autophagy support 45%, anti oxidant response 35%.

Matched peptides

Highest match first. The score is the share of this entry's targets the peptide carries; it is a match score, not a verdict.

PeptideHow it worksWhy it matches
FOXO4-DRI
Longevity & bioregulators
D-Retro-Inverso peptide that disrupts FOXO4-p53 interaction in senescent cells. In senescence, FOXO4 binds p53 at DNA-SCARS, preventing apoptosis. FOXO4-DRI: (1...senescence modulation, autophagy supportCompare & quote
Vilon
Immune & thymic
Shortest peptide known to have biological activity - just two amino acids. Derived from thymus tissue (component of Thymalin). Acts as epigenetic regulator - in...senescence modulation, autophagy supportCompare & quote
Livagen
Longevity & bioregulators
Khavinson tetrapeptide bioregulator derived from liver tissue extract amino-acid analysis (US 7101854); studied for hepatocyte functional activity and chromatin...senescence modulationCompare & quote
Ovagen
Longevity & bioregulators
Khavinson tripeptide bioregulator; studied in experimental kidney-function and renal cell-renewal models (peptide-db) and in ovarian/reproductive tissue regulat...senescence modulationCompare & quote
AHK
Longevity & bioregulators
Copper-binding tripeptide; the free (non-copper) form. Studied for hair-follicle dermal papilla proliferation and antioxidant activity; forms AHK-Cu with copper...anti oxidant responseCompare & quote
Epitalon
Longevity & bioregulators
Synthetic tetrapeptide based on epithalamin (pineal extract). Primary mechanism: telomerase activation. Increases telomerase activity in somatic cells, potentia...anti oxidant responseCompare & quote
L-Carnosine
Nootropic & neuro
Endogenous dipeptide found abundantly in muscle and brain tissue. Functions as intracellular buffer (histidine imidazole ring), antioxidant (metal chelation, RO...anti oxidant responseCompare & quote
L-Glutathione (reduced)
Other peptides
Master intracellular antioxidant. Tripeptide containing cysteine with free thiol group that serves as reducing equivalent. Detoxifies reactive oxygen species, m...anti oxidant responseCompare & quote
Melanotan I
GLP-1 & metabolic
Melanocortin receptor agonist; binds MC1R on melanocytes, activating adenylyl cyclase → cAMP → PKA → CREB → MITF → increased tyrosinase expression → eumelanin s...anti oxidant responseCompare & quote
SS-31
Other peptides
Mitochondria-targeting tetrapeptide that selectively binds to cardiolipin in the inner mitochondrial membrane. Stabilizes electron transport chain complexes, re...anti oxidant responseCompare & quote
Vesugen
Nootropic & neuro
Synthetic tripeptide bioregulator targeting vascular endothelium. Interacts with DNA at promoter regions, particularly Ki-67 gene, to stimulate endothelial cell...anti oxidant responseCompare & quote

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What the quotation does

For the peptides you pick it lists the products vendors in your country offer, each clickable, and ranks them three ways: best price (product price per mg), best value (price per mg after the water, syringes or needles the format forces), and best overall (value, days usable after opening, handling and quantity, weighted in the open). Every number's working is printed under it.

How the arithmetic works