Melanocortin Pathway Signaling
From the engine's documented indication list (thirty entries, curated 2026-02-23). Targets: melanocortin pathway 90%, arousal modulation 35%, appetite modulation 35%.
Matched peptides
Highest match first. The score is the share of this entry's targets the peptide carries; it is a match score, not a verdict.
| Peptide | How it works | Why it matches | |
|---|---|---|---|
| Melanotan II GLP-1 & metabolic | MC1R - melanogenesis; MC4R - sexual arousal; MC3R - appetite suppression | melanocortin pathway, arousal modulation, appetite modulation | Compare & quote |
| Bremelanotide Hormonal & reproductive | Bremelanotide is a cyclic heptapeptide melanocortin receptor agonist with high affinity for MC4R and MC1R. Unlike other melanocortins, it acts centrally in the ... | melanocortin pathway, arousal modulation | Compare & quote |
| Melanotan I GLP-1 & metabolic | Melanocortin receptor agonist; binds MC1R on melanocytes, activating adenylyl cyclase → cAMP → PKA → CREB → MITF → increased tyrosinase expression → eumelanin s... | melanocortin pathway | Compare & quote |
| Cagrilintide GLP-1 & metabolic | Long-acting acylated amylin analogue; non-selective agonist at amylin receptors (AMY1-3) and the calcitonin receptor. Slows gastric emptying, promotes satiety; ... | appetite modulation | Compare & quote |
| Liraglutide GLP-1 & metabolic | GLP-1 analog with 97% homology to human GLP-1(7-37). C16 fatty acid (palmitic) attached via glutamic acid spacer at Lys26 enables albumin binding for extended h... | appetite modulation | Compare & quote |
| Mazdutide GLP-1 & metabolic | appetite modulation | Compare & quote | |
| Oxytocin Nootropic & neuro | Nonapeptide neurohormone that binds oxytocin receptors (OXTR), activating Gq/11 signaling. In the CNS, modulates social behavior, trust, and bonding. Peripheral... | arousal modulation | Compare & quote |
| Retatrutide GLP-1 & metabolic | Investigational "triple agonist" that activates GLP-1, GIP, and glucagon receptors, aiming to reduce appetite/food intake, improve glycemic control, and increas... | appetite modulation | Compare & quote |
| Semaglutide GLP-1 & metabolic | GLP-1 receptor agonist - increases insulin, decreases glucagon | appetite modulation | Compare & quote |
| Tirzepatide GLP-1 & metabolic | GLP-1/GIP dual receptor agonist | appetite modulation | Compare & quote |
| VIP Other peptides | 28-amino acid neuropeptide that binds to VPAC1 and VPAC2 G-protein coupled receptors, activating adenylyl cyclase and increasing cAMP. Causes potent vasodilatio... | arousal modulation | Compare & quote |
What the quotation does
For the peptides you pick it lists the products vendors in your country offer, each clickable, and ranks them three ways: best price (product price per mg), best value (price per mg after the water, syringes or needles the format forces), and best overall (value, days usable after opening, handling and quantity, weighted in the open). Every number's working is printed under it.