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Sleep Optimization

From the engine's documented indication list (thirty entries, curated 2026-02-23). Targets: sleep architecture support 85%, circadian rhythm 75%, GABAergic 55%, arousal modulation 35%.

Matched peptides

Highest match first. The score is the share of this entry's targets the peptide carries; it is a match score, not a verdict.

PeptideHow it worksWhy it matches
DSIP
Nootropic & neuro
Neuropeptide affecting sleep architecture; exact mechanism unclear; may act via NMDA receptors; interacts with MAPK cascade; homologous to glucocorticoid-induce...sleep architecture support, circadian rhythm, GABAergicCompare & quote
Epitalon
Longevity & bioregulators
Synthetic tetrapeptide based on epithalamin (pineal extract). Primary mechanism: telomerase activation. Increases telomerase activity in somatic cells, potentia...circadian rhythmCompare & quote
Pinealon
Nootropic & neuro
Pinealon penetrates cell membranes and nuclear membranes to interact directly with DNA, regulating gene expression. Does not bind to cell surface or cytoplasmic...circadian rhythmCompare & quote
NA-Selank
Nootropic & neuro
N-acetylated version of Selank with enhanced stability and potentially different receptor binding. Anxiolytic heptapeptide derived from tuftsin with added Pro-G...GABAergicCompare & quote
Selank
Nootropic & neuro
Synthetic heptapeptide tuftsin analog; reported anxiolytic/nootropic activity with neuroimmune modulation (incl. effects on neurotransmitter systems and gene-ex...GABAergicCompare & quote
Bremelanotide
Hormonal & reproductive
Bremelanotide is a cyclic heptapeptide melanocortin receptor agonist with high affinity for MC4R and MC1R. Unlike other melanocortins, it acts centrally in the ...arousal modulationCompare & quote
Melanotan II
GLP-1 & metabolic
MC1R - melanogenesis; MC4R - sexual arousal; MC3R - appetite suppressionarousal modulationCompare & quote
Oxytocin
Nootropic & neuro
Nonapeptide neurohormone that binds oxytocin receptors (OXTR), activating Gq/11 signaling. In the CNS, modulates social behavior, trust, and bonding. Peripheral...arousal modulationCompare & quote
VIP
Other peptides
28-amino acid neuropeptide that binds to VPAC1 and VPAC2 G-protein coupled receptors, activating adenylyl cyclase and increasing cAMP. Causes potent vasodilatio...arousal modulationCompare & quote

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What the quotation does

For the peptides you pick it lists the products vendors in your country offer, each clickable, and ranks them three ways: best price (product price per mg), best value (price per mg after the water, syringes or needles the format forces), and best overall (value, days usable after opening, handling and quantity, weighted in the open). Every number's working is printed under it.

How the arithmetic works