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Type 2 diabetes

Named in the therapeutic-use field of Liraglutide. The first rows are the records that name it; the rest share their tags and are scored lower.

Matched peptides

Highest match first. The score is the share of this entry's targets the peptide carries; it is a match score, not a verdict.

PeptideHow it worksWhy it matches
Liraglutide
GLP-1 & metabolic
GLP-1 analog with 97% homology to human GLP-1(7-37). C16 fatty acid (palmitic) attached via glutamic acid spacer at Lys26 enables albumin binding for extended h...named in its registry recordCompare & quote
Semaglutide
GLP-1 & metabolic
GLP-1 receptor agonist - increases insulin, decreases glucagonshares the tags of the peptides that name it: appetite modulation, glucose homeostasis support, insulin sensitivityCompare & quote
Tirzepatide
GLP-1 & metabolic
GLP-1/GIP dual receptor agonistshares the tags of the peptides that name it: appetite modulation, glucose homeostasis support, insulin sensitivityCompare & quote
Dulaglutide
GLP-1 & metabolic
GLP-1 receptor agonist fusion protein. Activates GLP-1R coupled to adenylyl cyclase in pancreatic beta cells, increasing cAMP and leading to: (1) Glucose-depend...shares the tags of the peptides that name it: glucose homeostasis support, insulin sensitivityCompare & quote
Exenatide
GLP-1 & metabolic
Synthetic version of exendin-4 from Heloderma suspectum (Gila monster) saliva. 39-amino acid incretin mimetic with 53% homology to human GLP-1 but resistant to ...shares the tags of the peptides that name it: glucose homeostasis support, insulin sensitivityCompare & quote
Mazdutide
GLP-1 & metabolic
shares the tags of the peptides that name it: appetite modulation, glucose homeostasis supportCompare & quote
Retatrutide
GLP-1 & metabolic
Investigational "triple agonist" that activates GLP-1, GIP, and glucagon receptors, aiming to reduce appetite/food intake, improve glycemic control, and increas...shares the tags of the peptides that name it: appetite modulation, glucose homeostasis supportCompare & quote
Cagrilintide
GLP-1 & metabolic
Long-acting acylated amylin analogue; non-selective agonist at amylin receptors (AMY1-3) and the calcitonin receptor. Slows gastric emptying, promotes satiety; ...shares the tags of the peptides that name it: appetite modulationCompare & quote
GLP-1
GLP-1 & metabolic
Native incretin hormone secreted by intestinal L-cells. Binds GLP-1R on pancreatic beta cells, activating adenylyl cyclase → cAMP → PKA pathway. Physiological e...shares the tags of the peptides that name it: glucose homeostasis supportCompare & quote
MOTS-c
GLP-1 & metabolic
AMPK activation; Insulin sensitization; Metabolic regulationshares the tags of the peptides that name it: insulin sensitivityCompare & quote
Melanotan II
GLP-1 & metabolic
MC1R - melanogenesis; MC4R - sexual arousal; MC3R - appetite suppressionshares the tags of the peptides that name it: appetite modulationCompare & quote

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How the arithmetic works