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Cognitive decline

Named in the therapeutic-use field of Pinealon. The first rows are the records that name it; the rest share their tags and are scored lower.

Matched peptides

Highest match first. The score is the share of this entry's targets the peptide carries; it is a match score, not a verdict.

PeptideHow it worksWhy it matches
Pinealon
Nootropic & neuro
Pinealon penetrates cell membranes and nuclear membranes to interact directly with DNA, regulating gene expression. Does not bind to cell surface or cytoplasmic...named in its registry recordCompare & quote
Humanin
Nootropic & neuro
Reported cytoprotective peptide with anti-apoptotic signaling; described as interacting with apoptosis-related pathways and having neuroprotective and metabolic...shares the tags of the peptides that name it: neuroprotection, oxidative stress controlCompare & quote
L-Carnosine
Nootropic & neuro
Endogenous dipeptide found abundantly in muscle and brain tissue. Functions as intracellular buffer (histidine imidazole ring), antioxidant (metal chelation, RO...shares the tags of the peptides that name it: neuroprotection, oxidative stress controlCompare & quote
ARA-290
Nootropic & neuro
Synthetic 11-amino acid peptide derived from the helix-B domain of erythropoietin (EPO). Selectively activates the innate repair receptor (IRR), a heteromer of ...shares the tags of the peptides that name it: neuroprotectionCompare & quote
BPC-157
Nootropic & neuro
Synthetic peptide based on body protection compound from gastric juice. Pleiotropic effects: (1) Upregulates growth factor receptors, (2) Promotes angiogenesis ...shares the tags of the peptides that name it: neuroprotectionCompare & quote
Cerebrolysin
Nootropic & neuro
Complex mixture of 14,635 peptides (<10 kDa) from porcine brain. 25% peptides, 75% free amino acids. Contains fragments of tubulin, actin, myelin basic protein,...shares the tags of the peptides that name it: neuroprotectionCompare & quote
Cortagen
Nootropic & neuro
Khavinson tetrapeptide identified as a primary active component of Cortexin (bovine brain cortex peptide preparation); studied for neuroprotection and nerve rep...shares the tags of the peptides that name it: neuroprotectionCompare & quote
DSIP
Nootropic & neuro
Neuropeptide affecting sleep architecture; exact mechanism unclear; may act via NMDA receptors; interacts with MAPK cascade; homologous to glucocorticoid-induce...shares the tags of the peptides that name it: circadian rhythmCompare & quote
Dihexa
Nootropic & neuro
Small molecule peptidomimetic derived from angiotensin IV. Binds hepatocyte growth factor (HGF) and its receptor c-Met with high affinity. Promotes: (1) HGF/c-M...shares the tags of the peptides that name it: neuroprotectionCompare & quote
Epitalon
Longevity & bioregulators
Synthetic tetrapeptide based on epithalamin (pineal extract). Primary mechanism: telomerase activation. Increases telomerase activity in somatic cells, potentia...shares the tags of the peptides that name it: circadian rhythmCompare & quote
GHK-Cu
Healing & recovery
Collagen/elastin synthesis; Glycosaminoglycan synthesis; Anti-inflammatory; Antioxidant (SOD/catalase upregulation)shares the tags of the peptides that name it: oxidative stress controlCompare & quote
L-Glutathione (reduced)
Other peptides
Master intracellular antioxidant. Tripeptide containing cysteine with free thiol group that serves as reducing equivalent. Detoxifies reactive oxygen species, m...shares the tags of the peptides that name it: oxidative stress controlCompare & quote

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