Investigational for obesity/chronic weight management and metabolic disease
Named in the therapeutic-use field of Retatrutide. The first rows are the records that name it; the rest share their tags and are scored lower.
Matched peptides
Highest match first. The score is the share of this entry's targets the peptide carries; it is a match score, not a verdict.
| Peptide | How it works | Why it matches | |
|---|---|---|---|
| Retatrutide GLP-1 & metabolic | Investigational "triple agonist" that activates GLP-1, GIP, and glucagon receptors, aiming to reduce appetite/food intake, improve glycemic control, and increas... | named in its registry record | Compare & quote |
| Liraglutide GLP-1 & metabolic | GLP-1 analog with 97% homology to human GLP-1(7-37). C16 fatty acid (palmitic) attached via glutamic acid spacer at Lys26 enables albumin binding for extended h... | shares the tags of the peptides that name it: appetite modulation, glucose homeostasis support | Compare & quote |
| Mazdutide GLP-1 & metabolic | shares the tags of the peptides that name it: appetite modulation, glucose homeostasis support | Compare & quote | |
| Semaglutide GLP-1 & metabolic | GLP-1 receptor agonist - increases insulin, decreases glucagon | shares the tags of the peptides that name it: appetite modulation, glucose homeostasis support | Compare & quote |
| Tirzepatide GLP-1 & metabolic | GLP-1/GIP dual receptor agonist | shares the tags of the peptides that name it: appetite modulation, glucose homeostasis support | Compare & quote |
| AOD-9604 GLP-1 & metabolic | Mimics the lipolytic (fat-burning) C-terminal fragment of human growth hormone. Upregulates beta-3 adrenergic receptors in adipose tissue, enhancing lipolysis. ... | shares the tags of the peptides that name it: nutrient partitioning | Compare & quote |
| Cagrilintide GLP-1 & metabolic | Long-acting acylated amylin analogue; non-selective agonist at amylin receptors (AMY1-3) and the calcitonin receptor. Slows gastric emptying, promotes satiety; ... | shares the tags of the peptides that name it: appetite modulation | Compare & quote |
| Dulaglutide GLP-1 & metabolic | GLP-1 receptor agonist fusion protein. Activates GLP-1R coupled to adenylyl cyclase in pancreatic beta cells, increasing cAMP and leading to: (1) Glucose-depend... | shares the tags of the peptides that name it: glucose homeostasis support | Compare & quote |
| Exenatide GLP-1 & metabolic | Synthetic version of exendin-4 from Heloderma suspectum (Gila monster) saliva. 39-amino acid incretin mimetic with 53% homology to human GLP-1 but resistant to ... | shares the tags of the peptides that name it: glucose homeostasis support | Compare & quote |
| GLP-1 GLP-1 & metabolic | Native incretin hormone secreted by intestinal L-cells. Binds GLP-1R on pancreatic beta cells, activating adenylyl cyclase → cAMP → PKA pathway. Physiological e... | shares the tags of the peptides that name it: glucose homeostasis support | Compare & quote |
| HGH Fragment 176-191 GLP-1 & metabolic | C-terminal fragment of hGH believed to promote lipolysis and inhibit lipogenesis. Unlike AOD-9604, this is the unmodified linear fragment which may have differe... | shares the tags of the peptides that name it: nutrient partitioning | Compare & quote |
| IGF-1 LR3 Growth hormone axis | IGF-1 analog with 13 N-terminal extension peptide (MFPAMPLSSLFVNG) and Arg substitution at position 3. Designed to minimize IGFBP binding while maintaining IGF-... | shares the tags of the peptides that name it: nutrient partitioning | Compare & quote |
What the quotation does
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